diff --git a/docs/cog_guides/core.rst b/docs/cog_guides/core.rst
index 28ccbe206..50681102b 100644
--- a/docs/cog_guides/core.rst
+++ b/docs/cog_guides/core.rst
@@ -1829,7 +1829,10 @@ Commands to add servers or channels to the ignore list.
 
 The ignore list will prevent the bot from responding to commands in the configured locations.
 
-.. Note:: Owners and Admins override the ignore list.
+.. Note::
+
+    - Category ignores are ignored by user-installed commands
+    - Owners and Admins override the ignore list.
 
 
 .. _core-command-ignore-channel:
@@ -1850,7 +1853,10 @@ Ignore commands in the channel, thread, or category.
 
 Defaults to the current thread or channel.
 
-.. Note:: Owners, Admins, and those with Manage Channel permissions override ignored channels.
+.. Note::
+
+    - Category ignores are ignored by user-installed commands
+    - Owners and Admins override the ignore list.
 
 
 **Examples:**
diff --git a/redbot/core/_global_checks.py b/redbot/core/_global_checks.py
index c3994d554..9107240d8 100644
--- a/redbot/core/_global_checks.py
+++ b/redbot/core/_global_checks.py
@@ -5,4 +5,7 @@ from . import commands
 def init_global_checks(bot):
     @bot.check_once
     async def check_message_is_eligible_as_command(ctx: commands.Context) -> bool:
+        if ctx.interaction is not None:
+            # equivalent checks are performed by `RedTree.interaction_check`
+            return True
         return await ctx.bot.message_eligible_as_command(ctx.message)
diff --git a/redbot/core/_settings_caches.py b/redbot/core/_settings_caches.py
index 8fdc2a216..3c678b899 100644
--- a/redbot/core/_settings_caches.py
+++ b/redbot/core/_settings_caches.py
@@ -161,6 +161,8 @@ class IgnoreManager:
             discord.StageChannel,
             discord.ForumChannel,
             discord.Thread,
+            discord.Object,  # This is solely here for the purpose of User Installed Bots,
+            # See Red#6501 & ignored_channel_or_guild in redbot/core/bot.py for more details.
         ],
         check_category: bool = True,
     ) -> bool:
@@ -168,7 +170,9 @@ class IgnoreManager:
 
         cid: int = channel.id
         cat_id: Optional[int] = (
-            channel.category.id if check_category and channel.category else None
+            channel.category.id
+            if check_category and hasattr(channel, "category") and channel.category is not None
+            else None
         )
         if cid in self._cached_channels:
             chan_ret = self._cached_channels[cid]
diff --git a/redbot/core/bot.py b/redbot/core/bot.py
index 61dc118ce..d274526fd 100644
--- a/redbot/core/bot.py
+++ b/redbot/core/bot.py
@@ -819,6 +819,9 @@ class Red(
             Whether or not the message is eligible to be treated as a command.
         """
 
+        # NOTE: any changes to implementation here may need to be made
+        # in the `RedTree.interaction_check` as well
+
         channel = message.channel
         guild = message.guild
 
@@ -911,7 +914,18 @@ class Red(
             return True
 
         if isinstance(ctx.channel, discord.Thread):
-            channel = ctx.channel.parent
+            if isinstance(ctx, discord.Interaction) and ctx.is_user_integration():
+                ctx: discord.Interaction
+                # This is a user installed interaction, and thus... We're doomed!
+                # We must mock an object because we don't have the channel cached,
+                # and we are unable to fetch a full channel from the interaction
+                # #BlameDiscord, See Red#6501 for more details.
+
+                # LIMITATIONS: Due the fact that we don't know the categories either as they aren't...
+                # communicated in the interaction, we can't check for category ignores.
+                channel = discord.Object(id=ctx.channel.parent_id)
+            else:
+                channel = ctx.channel.parent
             thread = ctx.channel
         else:
             channel = ctx.channel
diff --git a/redbot/core/core_commands.py b/redbot/core/core_commands.py
index 93cacdeb8..854b2e1ff 100644
--- a/redbot/core/core_commands.py
+++ b/redbot/core/core_commands.py
@@ -5789,7 +5789,9 @@ class Core(commands.commands._RuleDropper, commands.Cog, CoreLogic):
 
         The ignore list will prevent the bot from responding to commands in the configured locations.
 
-        Note: Owners and Admins override the ignore list.
+        Notes:
+        - Category ignores are ignored by user-installed commands
+        - Owners, Admins, and those with Manage Channel permissions override ignored channels.
         """
 
     @ignore.command(name="list")
@@ -5821,7 +5823,9 @@ class Core(commands.commands._RuleDropper, commands.Cog, CoreLogic):
 
         Defaults to the current thread or channel.
 
-        Note: Owners, Admins, and those with Manage Channel permissions override ignored channels.
+        Notes:
+        - Category ignores are ignored by user-installed commands
+        - Owners, Admins, and those with Manage Channel permissions override ignored channels.
 
         **Examples:**
         - `[p]ignore channel #general` - Ignores commands in the #general channel.